Our system provides a wide range of web-based software products to support your clinical research study. It consists of a clinical trials management system (CTMS), a CRF/Form Designer for electronic data collection (EDC) and an electronic patient portal (ePRO).
The web-based CRF/Forms Designer is probably the most sophisticated forms designer available. It caters for the typical question types, and also has novel question types, like table-based questions (combination of text/radio/dropdown/checkbox/likert field questions in multiple fixed or dynamic rows), image mark, file upload and EEG node selection. Branching/skip rules can be implemented on individual questions, groups of questions and fields within table-based questions. And if you need a new feature or application, we can develop it for you!
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CRF Forms Designer (sophisticated!)
Study Arms/Events/Participant Types
Contacts & Meetings
Patient Telephone Contact Log
Pedigree Charting Tool
Export to GEDCOM format
ePRO (patient reported data)
Electronic Patient Diary
SAS Extract File
Study Arm Randomization
Protocol Design & Study Set-up
Links to PubMed and ClinicalTrails.gov
CRF version and data-edit history
No 3rd party license costs
Active Directory support
Paragraph field (text box)
Likert scale (range or slider)
Visual Analogue Scale
Message box (alert)
ICD9 & ICD10|
Email CRF/form response
Grid/Matrix Questions (with multiple columns)
Grid/Matrix Questions (with dynamic rows)
Sections of questions
Duration question (e.g. age)
Happy-Sad face question
Pain-scale (with faces)
VarTracker is a web-based tool for retrieving information on genetic variants and generating alerts when variant data changes. The end-user can search for variants of interest based on a RefSeq ID and a cDNA change, and the tool will search and extract data from a variety of public databases, such as ClinVar, NCBI Gene, UniProt, dbSNP, NCBI Books, PubMed, MalaCard, MyVariant, gnomAD, ExAC, Mutalyze and ENSEMBL. The system will then re-check these variants every 24 hours to see if any variant information has changed, and will alert the end-user of these changes.
CLIRINX provides sophisticated Artificial Intelligence (AI) tools for clinical research. Expert systems can be used to help with decision-making and solve complex problems in medical research. AI tools are computer applications that combine software and specialized information to imitate expert human reasoning and advice. We also have a knowledge base (KB) editor that allows you to define and store complex structured and unstructured information about a specific area of knowledge, called a knowledge domain. Whereas the expert system defines knowledge in terms of if-then rules, the knowledge base editor provides a curation tool where knowledge can be defined in terms of a hierarchy, attributes and facts.
The American College of Medical Genetics and Genomics (ACMG) has developed standards and guidelines for assessing the likelihood that a genetic variant in a particular gene is the cause of a person’s illness. In 2015, revised guidelines were published (Richards et al, 2015), and recommend the use of specific standard terminology to describe genetic variants that cause diseases. The recommendation also describes a process for classifying variants into categories based on criteria for types of evidence (e.g. population data, computational/predictive data, functional data, segregation data and de novo data). CLIRINX has developed a web-based system for genetic variant curation that also includes a calculator for classifying genetic variants based on pathogenicity and severity. Contact us for more information.
CLIRINX provides core IT expertise to academic medical research studies, including custom software development, informatics strategy and data management.
We help clients achieve their goals in medical research by providing a range of informatics and support expertise to simplify the research process
and deliver client projects on time while maintaining the highest quality standards.
Expertise we provide include Project Management, Software Development, Training, Informatics Strategy, Data Migration, Neuroimaging Processing, Medical Record Processing and RedCap Consultancy.
We are PMP certified by the Project Management Institute (PMI), and have years of experience managing complex IT projects across a broad range of industries. We are experts in a variety of PM methodologies, including waterfall and agile software development (and different flavors in-between). When it comes to managing your IT projects, we're considered the "safe pair of hands" to make sure your project succeeds spectacularly.
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